This makes me think that one possible reason we havent observed any alien life is that similar to how we may avoid any sort of development or encroachment in an area containing an endangered species, we may have been marked off as too fragile to interact.

And humans are an incredibly fragile species from the perspective of a space faring civilization. If a meteor hits our planet, we are basically done. And even if that doesn't happen, we can only acquire raw materials and energy from our own planet, so we may basically just tap out all our resources before we learn to acquire it from somewhere else.

And then there is the fact that we love blowing each other up, which may not be a common trait amongst intelligent species.