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A comment on Vitamin D uncorrelated with Covid severity in those of European descent. Parent comment

Re:Vitamin D uncorrelated with Covid severity in those of Eu... by wxnx on Wednesday January 20, 2021 @04:00PM (#25851929)
Mendelian randomization (MR; for the interested layman - the term for instrumental variables techniques when the instrument is genotype) is a well-founded research paradigm with several known potential flaws which I discussed in more depth in reply to another comment below. But, fundamentally I agree with your assessment that the study does not definitively answer the question. More generally, the articles I referenced in the other comment may be of interest to you as well - specifically around the reliability of MR studies in general.

[1] doi:10.1038/s41588-018-0099-7

[2] doi:10.1093/hmg/ddy163

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Re:Vitamin D uncorrelated with Covid severity in those of Eu... by tacitusarc on Thursday January 21, 2021 @09:55AM (#25859420)
Maybe I'm entirely misunderstanding the study but wouldn't we see the same results in a population that supplements vitamin d, or population that has vitamin d deficiency, or both?
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