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Re:Why cancer cells waste so much energy by inglor_cz on Friday January 15, 2021 @09:36AM (#25791391)
Well, that is why I linked to NIH rather than one scientist's blog.

Myers is very outspoken in his rejection of the idea, but even as an amateur I can see rhetoric sleights of hand in his argumentation. An example:

These “layers” don’t exist! When my car malfunctions, I don’t get a horse

Bad comparison, a car did not evolve from a horse, there is no mechanism for it to have a previous "horse layer".

Myers seems to hate the idea so much and return to it so often and with so many damnations and so few citations that it actually decreases his credibility in my eyes.

Re:Why cancer cells waste so much energy by benibela on Friday January 15, 2021 @09:45AM (#25791508)
When the escalator malfunctions, you get a staircase
Re:Why cancer cells waste so much energy by sjg007 on Friday January 15, 2021 @09:48AM (#25791546)
Well I wouldn't say the multicellular system is reverting to a single older cell phase per say. Rather it needs NAD+ so it optimizes for that. The cells also lose adhesion and then migrate so clearly there's some "programming exception" not being caught. I view the cell as a bunch of copy paste code that's had some degree of refactoring applied so there are different programs and control systems in operation at any given time. Sometimes these get activated or not repressed erroneously, sometimes the source code gets scrambled.