I acted as primary care giver for an elderly relative with alzheimer's, broken hip, and a few other problems as well as losing my father to brain cancer. Of course I care, but I just think that everyone focusing on Dr. Pausch's issue while ignoring everyone else's is ... bad.
Besides, I'm sorry, but if you think that life is some how a beautiful thing or that there is some sort of divine purpose to it all, see if you feel the same way when you have to watch a person you've known and loved your whole life shit themselves or scream at people who aren't there to show their spouse who died twenty years ago.
Nature's a bitch, god's an asshole, then you turn into worm food.
Fortunately, though people don't know it, we are free to make our own way, and don't have to be held up to anyone's dogma about how to live life. Or buy their books.
Randy was a decent, intelligent guy who got dealt a bad hand and made the best of it. He was more like one of us than your random celebrity. He was a hacker who had time to look back on his life through a different lens and share his thoughts. That's one reason I read his book -- a shared background. And remember, a significant part of his drive to leave his thoughts was a parting gift to his children who are too young to know him now. Doesn't take anything away from all the other people with things to say.
I think this is a similar phenomena that occurs when people will give money to Cripple Cat on the internet but not the real life injured animal. Or person for that matter.