Pfizer vaccine appears effective against mutation in new coronavirus variants

Re:Pfizer vaccine appears effective against mutation in new ... by maxerickson on Saturday January 09, 2021 @12:00AM (#25697272)

From the phase 3 trials you'd absolutely expect cases to occur after vaccinations. That's what the 95% efficacy after 2 doses means, that 5% of people had symptomatic infections.

Hopefully it is the case that the 5% are people that have a weak response to the vaccine and the remainder mostly aren't infectious. They can study this by monitoring for asymptomatic infections (I don't know if they are going to or not).

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Re:Pfizer vaccine appears effective against mutation in new ... by doktorhladnjak on Saturday January 09, 2021 @01:56AM (#25698140)

95% effectiveness does not mean 5% of people had symptomatic infections. It means there were 20 times more infections in the placebo group compared to control.

If you gave the vaccine to 1000 people and placebo to 1000 people, and 100 of the placebo and 5 of the treatment group got sick, that's 95% effective, as is if all 1000 in the control group got COVID and only 50 in the treatment group.

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Re:Pfizer vaccine appears effective against mutation in new ... by maxerickson on Saturday January 09, 2021 @07:38AM (#25699866)

Yep, thanks for clarifying.

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Re:Pfizer vaccine appears effective against mutation in new ... by TheGallopedHigh on Saturday January 09, 2021 @02:52AM (#25698487)

You’re saying the same thing as the parent comment.

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Re:Pfizer vaccine appears effective against mutation in new ... by dtech on Saturday January 09, 2021 @04:01AM (#25698782)

Parent said 5% had symptomatic infections, 50 in this example, while the correct number is 0.5% percent or 5 people.

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