> you can use the desktop client with your phone off, which is a major + imho

Indeed, if it has to go through my phone it's nigh unusable in my opinion. Wire and Element/Matrix handle this properly since they don't depend on a phone number in the first place (so no need to tie it to your phone), only Signal and Threema are somewhat of a pain in this regard since you need to link it, and only Threema absolutely requires your phone to be online all the time.