I've been a Threema user for over 7 years now and I have my most important contacts there.

Telegram is no E2E-Messenger. I know you can enable it per chat, but that's so solution. And groups are always not encrypted. Also they use some non-standard encryption. Why?

Signal needs my phone number. I dislike that idea.

I use Discord for anything unimportant. I prefer to not use it though. For voice I still prefer TeamSpeak, because of the end to end encryption and self hosting.

I don't know or don't use the others.