The last line of the article, "If you start with nothing, you’re forced to think about everything.", really sums-up for me one of the real benefits of a startup: you can start from scratch. There are no legacy systems to integrate, no "historical awkwardness" (well, it's that way because it's always been that way...), and no politics. You get a blank slate with a startup - every aspect can be thought about and done right (for all values of "right" that are valid at the moment the thinking is done). Time to innovate...