I almost quit caffeine in one year

Re:I almost quit caffeine in one year by dota_fanatic on Tuesday January 05, 2021 @11:36PM (#25654701)

Very interesting, anecdotally coffee always had a different effect compared to tea, this seems to be one important difference. Do you have any pointers for further reading regarding the half-life in the brain?

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Re:I almost quit caffeine in one year by eurasiantiger on Wednesday January 06, 2021 @04:39AM (#25656121)

Here’s a review that might lead you there:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520841/

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Re:I almost quit caffeine in one year by dota_fanatic on Wednesday January 06, 2021 @10:19AM (#25658460)

Thanks, that is a more general review than what I was able to find. I wasn't able to find anything agreeing with a half-life on the order of weeks, however. Is it possible you're mistaking the half-life of irreversible MAOI's (since it binds to the enzyme irreversibly, the half-life is essentially the lifetime of the enzyme, weeks) with reversible (minutes to hours), which seem to be the ones in coffee?

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Re:I almost quit caffeine in one year by eurasiantiger on Sunday January 10, 2021 @05:50AM (#25713339)

No; the study I remember looking at was about reversible MAOIs being stored in fatty tissues.

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