Messengers of hope: two mRNA Covid-19 vaccines herald a new era for vaccinology

Re:Messengers of hope: two mRNA Covid-19 vaccines herald a n... by tn890 on Wednesday December 30, 2020 @04:32AM (#25580100)

>Autoimmune reactions should happen in the short run, right?

I believe Pandermix took 6 months for narcolepsy to develop.

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Re:Messengers of hope: two mRNA Covid-19 vaccines herald a n... by learc83 on Wednesday December 30, 2020 @09:18AM (#25581867)

The important to thing to realize about Pandermix was that the rate of people impact was so small that even if we followed 50k phase 3 participants over 10 years, we wouldn't have uncovered the issue.

The narcolepsy issue was never going to be uncovered before it was rolled out large scale.

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Re:Messengers of hope: two mRNA Covid-19 vaccines herald a n... by toabi on Wednesday December 30, 2020 @05:47AM (#25580581)

According to https://journals.plos.org/plosone/article?id=10.1371%2Fjourn...

the onset judged by "first contact to health care" was much earlier.

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Re:Messengers of hope: two mRNA Covid-19 vaccines herald a n... by flobosg on Wednesday December 30, 2020 @06:02AM (#25580674)

There seems to be an early-onset but also long-standing effect, maybe due to circulating antibodies inducing the autoimmune response over time.

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Re:Messengers of hope: two mRNA Covid-19 vaccines herald a n... by zilian on Wednesday December 30, 2020 @07:46AM (#25581202)

This does not make sense to me. Your own antibodies triggering an autoimmune response ?

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