If that's generally true, the difference here would be that the part of the spike protein topology that is typically bound to other proteins in an actual infection would be accessible to the immune system in the case of a vaccination. I think that is where the differential risk could occur with a vaccination that wouldn't occur with an actual infection (however small that might be).
In my daughter's case, something happened when she was about 14 years old that caused her body to determine that the beta cells in her pancreas were invaders and have to die, so I'm just tuned into this kind of possible side effect.
If the virus is destroyed and released into the extracellular environment, its proteins can dissociate and are further fragmented and processed by the immune system. What’s usually presented to T cells are small antigen pieces as opposed to the whole virus/protein.
Virus takes over the cell, makes the cell to manufacture components of the virus and to assemble viruses, until this disrupts the cell so bad that the cell dies and typically bursts. Surely at this point, not only assembled viruses, but also components at different stages of production, are released?
https://en.wikipedia.org/wiki/Introduction_to_viruses#Life-c...
OT, but what does this mean or refer to? I'm curious :)
Corny but fun, they had a few good ones.
I was wrong, its the nucleocapsid protein, not the membrane one, but that's even weirder as the N protein is only found inside the virus particle..
Sure, but aren't the proteins produced by the vaccine virtually identical to the ones produced by the actual virus?
If so, the calculus looks like this:
1) Take the vaccine and accept the (unknown, but apparently quite small) probability that something in your body will react very negatively to the generated viral proteins.
2) Get the virus, accept the probability (also unknown, but the same as in 1) that something in your body will react very negatively to the viral proteins, plus accept the additional risk of being infected by the actual virus.
I guess the third possibility would be to refuse the vaccine and gamble that you won't get the virus, either.