Anti-diarrhoea drug drives cancer cells to cell death

Re:Anti-diarrhoea drug drives cancer cells to cell death by abruzzi on Wednesday December 23, 2020 @02:07PM (#25520906)

after an accident ~15 years ago, I was discharged after 6 months on 120mg of Oxycontin daily (40mg 3x a day) After being frustrated being tethered to the oxy bottle, I went cold turkey. The first thing that happened after the withdrawal symptoms subsided was I found I had chronic diarrhea. After years with my doctor trying different things, I found that the symptoms could be managed with about 16mg of loperamide. That was great for a while, until the FDA restricted the bottle size. At that point I could no longer buy enough over the counter, so I now have my doctor prescribing it for me. Unfortunately 16mg a day is the largest amount they can prescribe (IFAIK) so if it gets worse, I'll have to figure out another solution.

I'm not sure why this happened, but my suspicion is that while hospitalized I was infected by MRSA, and to try to get rid of it they were dumping some of the more toxic anti-bacterials into me to get rid of the MRSA (which took a year and a half to get rid of.)

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Re:Anti-diarrhoea drug drives cancer cells to cell death by throw345hn on Wednesday December 23, 2020 @02:43PM (#25521330)

Wow, cant imagine being in your situation. I would say try to ease yourself into lowering your dose slowly. I am not sure if its even possible with your situation but with IBS I try to control everything else including stress, food and sleep. I take loperamide if those dont work and it allows me to reset myself into being normal for sometime, that way I can retry. I try to go as long as I can without one and see if I can push myself. But I dont get too far due to work stress anyway.

Honestly the whole thing about people abusing it and FDA clamping down works against normal people who are genuinely using it.

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