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A comment on The opioid effects of gluten exorphins: asymptomatic celiac disease (2015). Parent comment

Re:The opioid effects of gluten exorphins: asymptomatic celi... by elhudy on Friday December 18, 2020 @09:45AM (#25467547)
If eating gluten is that unpleasant for you why wouldn't you get the biopsy? I would want to know 100%.

EDIT: in the absence of antibodies the biopsy would still show:

-Crypt hyperplasia with a decreased villi/crypt ration. Crypts are grooves between the villi, which are the small fingerlike projections that line the small intestine and promote nutrient absorption. Crypt hyperplasia is when the grooves are elongated compared to a normal intestinal lining which has short crypts.

-Blunted or atrophic villi. This is a shrinking and flattening of the villi due to repeated gluten exposure.

https://celiac.org/about-celiac-disease/screening-and-diagno...

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Re:The opioid effects of gluten exorphins: asymptomatic celi... by jamesgeck0 on Friday December 18, 2020 @12:52PM (#25469800)
> If eating gluten is that unpleasant for you why wouldn't you get the biopsy?

Because getting the test would require about a month of agonizing pain with constant diarrhea, perhaps? Just to get a formal confirmation of something they're already pretty sure of.

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Re:The opioid effects of gluten exorphins: asymptomatic celi... by elhudy on Saturday December 19, 2020 @10:55AM (#25478161)
Did you read my post? If you get a biopsy you don't necessarily need to eat gluten because the damage is visible.
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