Progress Toward a Safer Psychedelic Drug to Treat Depression and Addiction

Re:Progress Toward a Safer Psychedelic Drug to Treat Depress... by pmoriarty on Thursday December 10, 2020 @03:26PM (#25378148)

"Olson's team selected ibogaine because it seemed to have the most daunting side effects, including hallucinations and potentially fatal heart problems. It's also increasingly hard to find the plants that naturally contain ibogaine, and synthetic versions of the drug have been difficult to make in large quantities."

"These obstacles make ibogaine "the Mount Everest of psychedelics," Olson says."

Another candidate would have been datura and related plants.

[ Parent | on HN ]

Re:Progress Toward a Safer Psychedelic Drug to Treat Depress... by pstuart on Thursday December 10, 2020 @03:44PM (#25378373)

Datura is some scary shit. Way back in the days of "experimentation" jimsonweed was investigated by friends. In 2 of those cases they were literally hallucinating for over 24 hours -- not walls breathing stuff, literally living in a different universe.

Obviously there was recklessness involved, but it certainly made an impression on me.

[ Parent | on HN ]

Re:Progress Toward a Safer Psychedelic Drug to Treat Depress... by xyzzy123 on Thursday December 10, 2020 @03:56PM (#25378538)

Hallucinations are one thing.

If they took datura your friends most likely experienced delusions (aka distorted perceptions or thinking - and you believe it is real).

It's a really reckless thing to mess around with under almost any circumstances.

[ Parent | on HN ]

Re:Progress Toward a Safer Psychedelic Drug to Treat Depress... by pstuart on Thursday December 10, 2020 @04:13PM (#25378778)

It was reckless, and ill-informed to boot.

[ Parent | on HN ]