News for hackers. Stuff that matters.
Re:MDMA-assisted couples therapy investigated in pilot trial by twic on Wednesday December 09, 2020 @04:45PM (#25365656)
> But if you've ever done MDMA you'd certainly know it was a placebo

What's the dose used in the experiment? Similar to a recreational dose, or much smaller? If it was much smaller, i could imagine people not really being able to tell.

EDIT: The paper [1] says there are two MDMA 'sessions', about three weeks apart, and:

> Each partner was given 75 mg MDMA in the first MDMA session, and 100 mg in the second MDMA session, with an optional supplemental half-dose 1.5 hours later in both sessions (participants were informed that the supplemental half-doses could prolong the therapeutic window of MDMA effects).

I am told that a typical recreational dose of MDMA is 100 mg. More concretely, an Orange Tesla is ~250 mg, so make of that what you will.

[1] https://www.tandfonline.com/doi/full/10.1080/20008198.2020.1...

Re:MDMA-assisted couples therapy investigated in pilot trial by jcampbell1 on Wednesday December 09, 2020 @05:09PM (#25365955)
1mg per lb of body weight is about what is required to “roll” for a very infrequent user. I personally think it is a pretty ideal drug to use no more than twice per yer with a partner, and you sure as hell don’t want a therapist in the room, as it would waste the physical intimacy effects.
Re:MDMA-assisted couples therapy investigated in pilot trial by loceng on Wednesday December 09, 2020 @06:21PM (#25366899)
It depends what you're going for. Maps.org's research with MDMA-assisted psychotherapy for PTSD had incredible results. If you do it recreationally with a partner you'll become physical-intimate with, you'll be able to distract yourself away from yourself more - if doing it solo with guidance and support of someone else, you'll more be able to focus and process on thoughts/feelings/memories that come up. There's benefit and space for both.