Where I lived in Potrero and SoMa was absolutely not walkable. Potrero was particularly bad because any amount of walking meant climbing a very, very long and steep hill - as in by the time you make it up, you're sweating like crazy.
Castro and Haight/Ashbury were walkable, but nowhere as walkable as a city like NYC.
The middle ground for me was a motorcycle. Easy to park anywhere. Cheap. Great gas mileage, etc.
I had roommates working for Cisco in SoMa who took the bus to work. That was a constant topic of frustration for him. He ended up getting a motorcycle too because of the commute.
Berkeley's walkable area encompasses all of Telegraph Avenue down to Ashby (Berkeley Bowl) (South), all of downtown (West), the perimeter of the UC Berkeley campus and the campus itself, and probably half way down University avenue (further West), the North Berkeley area to the north of downtown Berkeley (Chez Panisse, etc...) (North). If you like walking, you can walk from campus all the way to the Bay. If you like hiking, you can hike up part of the way to the LBL. San Pablo Ave is also walkable but wasn't as ritzy.
The inaccessible directions are NE and E. W was considered ghetto but has gentrified. The only parts harder to walk are up in the hills (pretty much impossible: narrow, windy, steep, no sidewalks) (E) and the hilly parts of North Berkeley (NE).
Is this true? I've only visited the bay for a total of 15 days but only SF and parts of Oakland seemed walkable.