As book store owner, I really think it's an irrational decision to invest heavily in fighting Amazon. You're chances of success are pretty slim.
As for big businesses ? Well, there's Walmart, Target.
In the end, the e-commerce industry is a place where most of the market share would be controlled by a few large companies. That was clear from the beginning.
This again, is glib.
To suggest that you somehow know all these vendors have 'not tried anything'.
How about lobbying government to subsidize their business like the US Government subsidizes delivery? Or the VAT tax breaks that Amazon gets? Or the fact that Amazon is dumping merchandise on the US by selling for negative margins, paid for by profits out of AWS?
A local bookstore has 6 staff. They have no power.
https://www.businessinsider.com/jeff-bezos-amazon-history-fa...
Even big businesses facing Amazon have done very little to compete.