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Re:Manawyrm/ISA8019 – RTL8019-based ISA network card, NE2000... by tannhaeuser on Thursday December 03, 2020 @04:25PM (#25295243)
Was a long time since I last heard about NE2000. Getting flashbacks of me creating NetWare 2 images with Novell linker, disk-jockeying 5,25" floppies while making notes about jumpers for IRQ and I/O address, trying to bind AppleTalk cards for IPX and TCP/IP, etc.

Is there even a new x86 ISA system that you could buy today?

Re:Manawyrm/ISA8019 – RTL8019-based ISA network card, NE2000... by dogecoinbase on Thursday December 03, 2020 @04:53PM (#25295685)
There are quite a few, mostly meant for industry applications where there is a controller card for a specialized device, e.g.: https://www.nixsys.com/motherboard-with-isa-slot/

Though you'll find that a lot of them are single-board computers meant to interface with a bus backplane, either PC/104 (as the sibling comment notes) or... more advanced, like this thing: https://www.advantech.com/products/1-2jkn6l/pca-6028/mod_e93...

which will accept aCore i7s and 16GB of RAM, and has native ISA.

Re:Manawyrm/ISA8019 – RTL8019-based ISA network card, NE2000... by EvanAnderson on Thursday December 03, 2020 @04:32PM (#25295355)
There are still 486-class single board computers (SBC) available w/ PC/104 interfaces (which is electrically the ISA bus but on a pin header). I believe there are boards that let you interface card-edge connector slots to a PC/104 SBC.
Re:Manawyrm/ISA8019 – RTL8019-based ISA network card, NE2000... by rzzzt on Thursday December 03, 2020 @05:09PM (#25295875)
LGR has made a video recently, installing one (it had an ISA edge connector, not PC/104) with a backplane in a desktop case: https://youtu.be/Q4qJf50YSVk