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A comment on Pfizer Covid vaccine approved for use next week in UK. Parent comment

Re:Pfizer Covid vaccine approved for use next week in UK by apexalpha on Wednesday December 02, 2020 @06:51AM (#25275538)
Yes, this is why these mRNA vaccines are here so fast; a lot of prework was done for SARS vaccine, which is also a Corona disease.

But I think SARS died out before the vaccine was ready/needed.

[ Parent | on HN ]
Re:Pfizer Covid vaccine approved for use next week in UK by patall on Wednesday December 02, 2020 @07:29AM (#25275744)
the parent is concerned regarding the appearance of ADE (Antibody-dependent enhancement) during the creation of the SARS vaccine.

While we cannot totally disregard ADE, I assume we should have seen it by now (and the Oxford trial was stopped exactly because they thought they might have observed something like it). Whether it appears again on a population scale level, nobody knows.

[ Parent | on HN ]
Re:Pfizer Covid vaccine approved for use next week in UK by jonstaab on Wednesday December 02, 2020 @04:30PM (#25281902)
I don't know anything, but I've read that ADE can take 1-3 years to surface.
[ Parent | on HN ]
Re:Pfizer Covid vaccine approved for use next week in UK by SomeoneFromCA on Wednesday December 02, 2020 @11:33AM (#25278047)
Yeah, I've thought about it too, but both mild reinfections and vaccine trials show that SARS-2 does not exhibit ADE.
[ Parent | on HN ]