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Re:Run Homebrew Natively on Apple Silicon Arm M1 by grey-area on Monday November 23, 2020 @08:42AM (#25186630)
The problems with homebrew packages at present are mostly down to projects like Go and Rust not being updated for M1 ARM yet and hence sources not compiling properly rather than a problem with homebrew itself. So users attempting to compile from original upstream sources would run into similar problems.

They have an overview issue here:

https://github.com/Homebrew/brew/issues/7857

Re:Run Homebrew Natively on Apple Silicon Arm M1 by steveklabnik on Monday November 23, 2020 @09:27AM (#25187041)
Rust does have tier 2 support, but it hasn’t made its way to stable yet. This means if you did try in upstream today, it would work.