Vit-D in asymptomatic and critically ill Covid-19 patients and correlation

Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by anonuser123456 on Sunday November 22, 2020 @12:54AM (#25175268)

Obesity lowers serum concentrations of Vitamin-D. We know obesity is strongly correlated with severe covid. So not really that interesting of a correlation IMO.

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Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by oieoeireoes on Sunday November 22, 2020 @01:16AM (#25175378)

Yes, D is fat-soluble, so it won't increase much in serum levels until the fat is saturated with it.

But your criticism doesn't necessarily check out as the average BMI of group B was actually lower than that of group A.

See page 4 of the PDF [1].

[1]: https://www.nature.com/articles/s41598-020-77093-z.pdf

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Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by gfodor on Sunday November 22, 2020 @12:56AM (#25175288)

Any correlation where one can change one of the variables by taking a cheap, safe pill is interesting, unless we can show which way the causality goes.

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Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by anonuser123456 on Sunday November 22, 2020 @01:14AM (#25175365)

Well... taking that cheap pill in a blind RCT would show the arrow of causality.

People have known about this correlation for months now. If it were really a thing, clinicians would be publishing case studies like crazy of successful treatment with vitamin-D. I'm not seeing that in the literature... so I doubt it will pan out.

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Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by oieoeireoes on Sunday November 22, 2020 @01:41AM (#25175489)

I also wouldn't expect much from giving D3 in a hospital setting since it takes time for D3 supplementation to affect serum levels.

That's why the MATH+ protocol [1] recommends Calcifediol or Cholecalciferol. According to their own review [2] the protocol reduces hospital mortality from 20-30% to about 5%.

[1]: https://covid19criticalcare.com/math-hospital-treatment/pdf-...

[2]: https://covid19criticalcare.com/math-hospital-treatment/scie...

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Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by geomark on Sunday November 22, 2020 @02:00AM (#25175562)

Tangential question: How long does it take exposure to sunlight to affect serum levels?

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Re:Vit-D in asymptomatic and critically ill Covid-19 patient... by kevinmchugh on Sunday November 22, 2020 @01:15PM (#25179559)

Depends on latitude, season, and melanin, as I understand it

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