Generally, it's been pretty easy to transition for me, but I used to rely on things like the automatic nginx image that you need to mount the docker socket into so it can route traffic to containers when they come up. Since there's no daemon, there wasn't a way to do that. I think people are working on it, but I haven't tried recently.

Work also uses a special docker RUN command that can use the host's ssh keyring to, eg. Install something from a private github repo. Doesn't seem to exist in podman.