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Re:Chronic alcohol use reshapes the brain’s immune landscape by treeman79 on Wednesday November 18, 2020 @02:42PM (#25141444)
Fun fact. My blood clots super easy. Genetic issue. (Factor 5) This is important.

Also most of family going back at least 3 generations are alcoholics.

  For many years I had this weird sense that alcohol cleared up my head.    But didn’t last long, and felt like crap later, so I almost never drink.  Plus, watching family die young is good motivation to stay away.
Eventually ended up on Blood thinners, wow. Brain fog gone in days.

So I have a pet theory that the reason a lot of my extended family fell into alcoholism is because it was a way to manage the disease even though they didn’t know they had it.

Re:Chronic alcohol use reshapes the brain’s immune landscape by boringg on Wednesday November 18, 2020 @03:11PM (#25141807)
I feel like this is the kind of thing that medicine just misses completely. I like that kind of theory and I'm glad you've found relief.
Re:Chronic alcohol use reshapes the brain’s immune landscape by treeman79 on Wednesday November 18, 2020 @03:26PM (#25141993)
Thanks! My second pet theory, is that a LOT of the keto/paleo/vegan etc diets are popular because of undiagnosed autoimmune conditions.

Been reading through support groups for years now. A noticeable cohort of people find relief via diet. Sugar=bad, mostly. But even things like tomatoes sometimes need to go.

Or conversely that the standard America Diet is so horrible, that if you have any possibility of an autoimmune condition, then diet will push you over the cliff.

Re:Chronic alcohol use reshapes the brain’s immune landscape by qeternity on Wednesday November 18, 2020 @07:44PM (#25144822)
It’s not autoimmune. It’s inflammation. I have been eating LCHF for a decade now and it started with reading about eggs and cholesterol intake. Once I read about the drivers of serum cholesterol, and the interplay between glucose and insulin, it became pretty obvious that carbohydrates, in the quantities and concentrations that many people consume them, are genuinely poisonous.
Re:Chronic alcohol use reshapes the brain’s immune landscape by boringg on Wednesday November 18, 2020 @09:18PM (#25145473)
Expand on drivers of serum cholesterol please...
Re:Chronic alcohol use reshapes the brain’s immune landscape by qeternity on Saturday November 21, 2020 @01:51PM (#25171798)
BMI and glucose levels