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Re:Moderna Covid vaccine candidate almost 95% effective, tri... by jariel on Monday November 16, 2020 @08:17AM (#25111246)
Correct me if I'm wrong but colds are a grab bag of a variety of ever mutating viruses. So we could nail one but not the other 500.
Re:Moderna Covid vaccine candidate almost 95% effective, tri... by thechao on Monday November 16, 2020 @08:55AM (#25111614)
There's about 40, not 500; and it is tractable. Search for the section on 'common cold' in the following article:

https://www.houstonchronicle.com/life/article/COVID-vaccine-...

Re:Moderna Covid vaccine candidate almost 95% effective, tri... by CodeGlitch on Monday November 16, 2020 @08:22AM (#25111300)
Yes I agree - but I read this [1] today, which talks about "universal" vaccines.

"RNA and DNA vaccines are so far experimental, but trials have been promising and many scientists believe it could be one of those two types that will be the model that goes into mass production to protect against COVID-19.

The attraction, say experts, is that they will potentially offer a step towards something that has been the holy grail of vaccine design – the universal vaccine.

The vaccines being trialed by the team from Pfizer, which tests show provides protection in 90% of cases, and from Moderna, which shows efficacy of 94.5%, are RNA vaccines. If either proves to be the winner in the race for a COVID vaccine, it will represent a seismic shift in vaccine technology."

[1] https://news.sky.com/story/coronavirus-how-vaccine-research-...

Re:Moderna Covid vaccine candidate almost 95% effective, tri... by JackC on Monday November 16, 2020 @09:01AM (#25111682)
Interesting. The next paragraph explains more what they mean by that:

"Jeffrey Almond, a visiting professor of microbiology at William Dunn School of Pathology, University of Oxford, told Sky News: 'All the current vaccines we have: diptheria, whooping cough, polio, measles, papillomavirus, you name it; all of them are very different. You don't have a generic process to make them. You have a dedicated factory, a dedicated process, very different technologies.

"'What RNA and DNA offer is an escape from that. We can make the RNA by a single process in a single factory. All we have to do is change the sequence of the RNA or DNA.'"

Very cool, but not necessarily "universal" in the sense you'd need to target all the different rapidly-mutating cold viruses.

Re:Moderna Covid vaccine candidate almost 95% effective, tri... by ericb on Monday November 16, 2020 @06:36PM (#25118511)
> "We can make the RNA by a single process in a single factory. All we have to do is change the sequence of the RNA or DNA."

That's really interesting! Imagine RNA vaccine creation "as a service." Researchers order fully-formed injectable vaccines for animal trials just by submitting a sequence. It would be like AWS for vaccines.

Re:Moderna Covid vaccine candidate almost 95% effective, tri... by bluGill on Monday November 16, 2020 @09:47PM (#25119778)
No, the hope is even greater: your doctor orders a fully formed injectable vaccine for the specific cancer that is currently growing in your body. Nobody else has exactly that same mutation, so there is no point in animal trails as the vaccine will only be helpful to you.

This vaccine is a great help to the above: it proves conclusively that the idea is sound. Probably future mRNA vaccines can skip all the phase 1-2 trials and go directly to 3. And for rare diesease they can even skip phase 3.