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So unless I scoot the laptop off-axis or I have to move my hands off axis to type.
I'm unsure how this isn't unergonomic. It's not something to get used to. It's bad design. Period.
I haven't used a Mac in years but the one thing they always nailed was the trackpad. It's big and actually centred on the laptop body.
It’s much easier and more comfortable to adjust my hands over a slightly offset keyboard.
I gave it a try for one minute when I unpacked my new laptop in 2014 and I immediately shifted it to the right: typing as you suggest was terrible for wrists, shoulders and probably the spine.
My workaround: I move the windows I work more often (eg: the editor) to the left part of the screen.
To be fair: there is no way to fix an ergonomically broken design. There are only mitigations and those a probably subjective: everybody is a little different and muscles/skeletons/etc can accommodate different twists.
Those are laptops with numeric keypads, the trackpad is still centred relative to the "main area" of the keyboard (the home row and in particular the rest keys - the two keys with a little bump, F and J on a QWERTY) but it is off-centre relative to the body of the laptop due to the presence of the keypad.
Macs don't have numpads so if you've always used Macs it's understandable that you're not familiar with this type of layout.
In any case that type of placement makes no difference while you are using the laptop, because keys and touchpad are still where they are supposed to be relative to each other.