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Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by refurb on Tuesday November 10, 2020 @03:17AM (#25043779)
Because it degrades at higher temperatures.

They do stability studies on these molecules, holding samples at different temperatures and measuring how much "is left" after a period of time.

This particular RNA sequence and carrier might be particularly unstable, so it require -80C if you want it to last longer than a few weeks.

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