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Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by johnisgood on Monday November 09, 2020 @05:12PM (#25040566)
How do we know that there are no significant long-term side-effects? These vaccines seem to be developed so quickly while others take years or even decades... I do not know if this is irrational fear, but I fear that this is rushed and there might be potentially serious side-effects that are missed.

Why am I being down-voted? Is it really of no concern?

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by XorNot on Monday November 09, 2020 @09:25PM (#25042284)
Short-answer: we don't and can't, since you'd need to use the vaccine for a long time.

Better answer: the vaccines are new but the individual systems used to develop them are not, and we have historical trials of a lot of the same techniques which show no long term risks. The biggest unknown has always been the risk of triggering a short-term, unexpected primary immune response that causes harm to the recipient. In the vaccines being developed, that has generally not been found to be the case, and since they're based on the virus currently infecting people we would not expect a response worse then that (which is to say: the components of vaccine use are all well studied, these are understood and safe materials).

The other issue is when we talk about "rushing" vaccine research, this does not involve shirking safety research - i.e. consider the influenza vaccine which year over year is basically a new vaccine we develop quite quickly. What it does mean is that you overlap the stages of vaccine development: normally if you have a P3-trial vaccine, you'd wait till that trial was successful before building the factory to make it. Instead, companies are being paid (or paying themselves) to build facilities and scale up production as soon as they get to the P3 trial stage - financially it's a huge risk, since what they have might not work, or might have an unacceptable risk profile in those trials - which means all the investment is a dead-loss.

This is where government steps in (and has stepped in in places): by guaranteeing the investment on getting those facilities out, it means if your vaccine works then you're ready to go and it's in production right away - as opposed to being another year to 2 years down the line while you work on manufacturing.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by minerjoe on Monday November 09, 2020 @06:47PM (#25041360)
I just ignore the down votes. You probably hitting the target.

This is of concern. The medical industry has a history of covering up the direct know effects of their medicine, AKA poisons. That system has been know for a very long time to lead with arrogance and it sometimes takes them a very long time to pull things they know are killing people. Its just too much $$$.

See vioxx and merck, for just one example.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by apostacy on Monday November 09, 2020 @06:40PM (#25041315)
I for one agree with you. There is no rush to get vaccinated.

Personally, I doubt I will get it at all. The authorities have a very long way to go to win back my trust, after the chain of screwups over the last year.

We've seen that they will lie to us, we've seen that they apply rules to us that they themselves don't follow, and we've seen them take advantage of the situation for their own benefit.

It is a huge shame that so many people are not going to take it solely because they've betrayed our trust so many times that now that they might be doing something good, we won't cooperate.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by johnisgood on Tuesday November 10, 2020 @12:20PM (#25048388)
You are getting down-voted too by people who do not even bother replying, probably some blind followers, government-loving NPCs.

You know how you could turn this against them to make them think twice about it? Get the Russian vaccines, or the Chinese. Yeah, do it! Suddenly they are not so keen... Now imagine if their beloved State made it mandatory to get Russian vaccines inside them. They would most likely be against it, and our votes would not be down... It is not even the votes I give a damn about, but the fact that we do not know THAT much of COVID-19 but people seem to believe the claims that we have extremely safe vaccines ready just within a few months. Yeah, they say that of the Russian vaccines, too, are you going to take it, down-voter? Would you like the State to make it mandatory for your kid to get vaccinated? I am curious.

My entire family tested positive for COVID-19, and my grandma most likely has it. None of us has/had symptoms. I do not want to get vaccinated. If you (not you, the down-voters) really care, go get vaccinated by the Russian vaccines.

My country plans to vaccinate the elderly, kids, and people with chronic diseases first, then the rest of the population. I really, really wonder how many people are going to have FORESEEABLE side-effects. I think they are also planning to make it mandatory.

P.S. I am not an anti-vaxxer, but these claims by pharmaceutical companies sound shady as heck. If they said they found the vaccine after 5 days and they claim it is super safe because 5 people did not die from it within 10 days, would it make you OK the vaccine? Come on. My problem is that. It is too quick, and too many promises of lack of side-effects, and lots of financial interest. For that I do not believe them. We (medical workers) even have to lie about people dying from COVID-19 so we (the hospital) get more funding. How about that? Governments put price control on the tests, which resulted in zero competition as it was not worth it for private businesses to continue testing. How about that?