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Re:AMD Reveals the Radeon RX 6000 Series, Coming November 18th by wongarsu on Wednesday October 28, 2020 @01:52PM (#24921910)
As a company we operate a server with consumer cards. Running your own consumer Nvidia cards is very cheap compared to buying time on servers with enterprise Nvidia cards. On the cloud you are paying a premium for being on the cloud, and on top of that the premium for having datacenter-licenced cards.

Of course this calculation depends on how bursty your compute requirements are and how much you pay for electricity (datacenter cards are more power efficient)

Re:AMD Reveals the Radeon RX 6000 Series, Coming November 18th by chrisjc on Wednesday October 28, 2020 @01:56PM (#24921951)
Isn't the proximity of your compute to your data a huge consideration too? I imagine that the egress data costs (cloud storage to your local GPU) could grow quite significantly if you're crunching enough data.

I guess if you're rolling your own compute clusters, you've probably rolled your own storage solution too?