1. Gaming. Just about nobody games on Linux with nVidia. Most people I know who game (from Linux) with nVidia GPUs use PCI passthrough to a guest VM running Windows. Very few use nVidia GPUs on their host system. My primary setup is a 2950x/128GB DDR4/Vega 56/2080 Super -- the latter goes to kvm exclusively.

2. "Research" such as machine learning. You don't need Wayland or X11 for this, and the proprietary drivers work the best. To be honest, this is a space where Ubuntu Server performs best. I keep one of these around in a VM (see above) for this purpose. (Mining also goes in this category)

Everything else can probably be done with an Intel or AMD GPU tbh.