Kambo, a properly dosed frog poison applied to the limbic system by first searing small dots through top layer of skin, has a similar effect by strongly engaging the immune system once it detects the poison - and causes a whole body reaction where the limbic/lymphatic system rapidly clears out the poison (and whatever other stagnant toxins are in the system), dumping them into the stomach which then have to be thrown up to clear them.

There are trained/certified shamans who offer kambo ceremonies.