I'm presuming you are talking about a generic "you", and not referring to me personally, because I've been working in (mostly) mission-driven companies for a decade. I do take a hit on my compensation and wealth for it, with my spouse and children by my side the whole time.

But granted, mission-driven people are less common. To the point that many people who are not fundamentally mission-driven truly do not comprehend that some of us are. We all have our own motivations.