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Re:Ask HN: Software for Reading Pdfs? by Jtsummers on Monday September 14, 2020 @05:33PM (#24475421)
Maybe Polar [0] would suit your needs, I have no idea how it does with TTS. I'm assuming by native you mean "runs on your hardware not a web app". It's native for desktop OSes, not for mobile and they have a syncing service between your devices.

On my iPad I've long been a fan of GoodReader, again I've never tried TTS with it.

[0] http://getpolarized.io/

Re:Ask HN: Software for Reading Pdfs? by Jugurtha on Monday September 14, 2020 @12:12PM (#24471857)
Re:Ask HN: Software for Reading Pdfs? by thesuperbigfrog on Monday September 14, 2020 @02:47AM (#24467494)
Native for what platform? Are you on Windows, MacOS, Linux, BSD, iOS, iPadOS, Android, etc. ?
Re:Ask HN: Software for Reading Pdfs? by theSealedTanker on Monday September 14, 2020 @08:39PM (#24476722)
If you are using linux, try Zathura
Re:Ask HN: Software for Reading Pdfs? by approxim8ion on Wednesday September 16, 2020 @01:49PM (#24495209)
+1 for Zathura. I use it for reading PDF and CBR and it's great. Minimal and vi keybindings.