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A comment on AstraZeneca Covid-19 vaccine study put on hold due to suspected adverse reaction. Parent comment

Re:AstraZeneca Covid-19 vaccine study put on hold due to sus... by xlm1717 on Wednesday September 09, 2020 @12:10AM (#24417037)
Biology is too "complicated" for our intelligence at least.
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Re:AstraZeneca Covid-19 vaccine study put on hold due to sus... by ethbr0 on Wednesday September 09, 2020 @06:56AM (#24419646)
His point was more along the lines of it being poorly designed.

Evolution isn't going to nicely separate functionality into clean, single-purpose biochemical pathways.

It's going to overload something that it already has to support a new feature, leading to a rat's nest of intertwined effects.

The hard part in drug development isn't affecting your target: that's pretty easy to guarantee with modern tools. It's finding out that that target also governs 10 other, completely unrelated bodily functions.

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Re:AstraZeneca Covid-19 vaccine study put on hold due to sus... by landryraccoon on Wednesday September 09, 2020 @01:43PM (#24423609)
> It's going to overload something that it already has to support a new feature,

Some companies in the valley just call that Wednesday.=)

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Re:AstraZeneca Covid-19 vaccine study put on hold due to sus... by ethbr0 on Wednesday September 09, 2020 @02:05PM (#24423889)
Absolutely, which gives me a chuckle when people trivialize biology, but run screaming from a (gasp!) 20 year old legacy codebase.
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