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A comment on AstraZeneca Covid-19 vaccine study put on hold due to suspected adverse reaction. Parent comment

Re:AstraZeneca Covid-19 vaccine study put on hold due to sus... by anonuser123456 on Tuesday September 08, 2020 @11:49PM (#24416872)
Your understanding of the immune system is not quite correct. Just because you can't detect antibodies doesn't mean you lack immunity.

B-cells can stop producing antibodies and reactivate production in response to an antigen. T-cell memory appears to be quite robust for coronaviruses (and this one in particular)

To establish a lack of durable antibody response, challenge trials would need to be done, where the host is challenged by the virus (or something that looks like the virus like it's spike protein). These trials have not been run.

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Re:AstraZeneca Covid-19 vaccine study put on hold due to sus... by kuhewa on Wednesday September 09, 2020 @09:19AM (#24420687)
We can only guess without data specific to SARS-COV-2, but for seasonal coronaviruses, antibodies disappear after ~6 months and reinfection with the same strain can occur after 1 year.
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