I had those experiences repeatedly (shrooms, which should be +-same), but always alone. I can't imagine doing that journey with anybody else, even close girlfriend, it would be just negative interference and distractions. In fact, I lost all my regular senses, laying on the bed, listening to very nice shamanic music (that must have helped a bit). I understood where religion comes from, or so it seemed to me at that time. At the end of the trip I had spiritual experience without any classical presence of god, at the end just chemicals going haywire in my brain.

By huge margin consistently the most intense experience in my life, and I've been through some stuff (birth of my son, 6 months backpacking in Himalaya, adrenaline/mountain sports, not in that order).

That was some 10 years ago, I don't even feel the need to try again. Kind of lesson took, not much more to gain, only risking some bad drama.