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Re:The First Randomized Controlled Trial on Vitamin D and Co... by mrslave on Thursday September 03, 2020 @09:09PM (#24370768)
IIRC, calcium toxicity is serious, but only a consequence of sustained Vitamin D supplementation.

Also there's some Joe Rogan-esque "just take the 5000 IU bro" even though 4000 is the recommended supplement upper bound. And devaboone warns against even using that much.

Re:The First Randomized Controlled Trial on Vitamin D and Co... by toto444 on Friday September 04, 2020 @08:25AM (#24374300)
The information can be a bit confusing though.

For breastfed babies, France recommend an intake of 25µg to 30µg but it's half of that in the UK (8.5 to 10µg).

Re:The First Randomized Controlled Trial on Vitamin D and Co... by me_me_me on Friday September 04, 2020 @06:11AM (#24373544)
Taking more than recommended is ok, your body will flush it out.

It is basically wasteful, only in extreme cases you could 'overdose' vitamins.

https://en.wikipedia.org/wiki/Vitamin_D_toxicity

Re:The First Randomized Controlled Trial on Vitamin D and Co... by curryst on Friday September 04, 2020 @10:49AM (#24375398)
> Taking more than recommended is ok, your body will flush it out.

This is not true. Vitamin D is fat-soluble, not water-soluble. Your kidneys can only filter out water-soluble vitamins. B vitamins are water-soluble; that's why there's practically no upper limit to how much you can take. Your kidneys will filter out the extra (assuming you aren't eating buckets full of the stuff).

Vitamin D toxicity occurs specifically because your body can't remove the excess vitamin D stored in your fat.

That's also why severe overdose happens over time, as opposed to instantly. You have to take a huge amount of Vitamin D at once to overdose (like millions of IUs) but you can cause toxicity using smaller doses over longer periods of time. If your body could flush it out, that wouldn't be true. Any excess would be removed and you would start each day "fresh".

Re:The First Randomized Controlled Trial on Vitamin D and Co... by valarauko on Friday September 04, 2020 @01:43PM (#24377161)
What's the mechanism for "flushing out" excess Vitamin D? The Wikipedia article you've linked offers no such mechanism for dietary Vit D. If anything, the article suggests that toxicity is only really possible through oral supplementation.