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Re:The First Randomized Controlled Trial on Vitamin D and Co... by JumpCrisscross on Thursday September 03, 2020 @08:12PM (#24370345)
> too high Vit D dose can cause problems

Many over-the-counter vitamin D supplements appear dosed for people with problems absorbing the chemical.

Re:The First Randomized Controlled Trial on Vitamin D and Co... by LegitShady on Thursday September 03, 2020 @08:59PM (#24370708)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210929/

Not really. It depends on the person obviously but the recommended values are too low due to statistical errors.

Up to 4000 iu per day likely ok.

Re:The First Randomized Controlled Trial on Vitamin D and Co... by t0mas88 on Friday September 04, 2020 @08:06AM (#24374184)
In the Netherlands the recommended intake is 5 mcg, that's equivalent to 200 iu. As far as I understand the US recommends 600.

Both are very far below the 4000 that's often cited here. So I think that 4000 is not a recommended intake but a limit before it becomes risky. For normal people it doesn't make sense to then aim for that maximum dosage.

Re:The First Randomized Controlled Trial on Vitamin D and Co... by curryst on Friday September 04, 2020 @10:56AM (#24375474)
The last I heard, the human body needs/consumes ~700 IU of Vitamin D per day. So I think your US levels are actually the full intake.

One thing to consider is biological inefficiency. A 4,000 IU capsule contains 4,000 IUs, but that doesn't mean your body can't actually extract all 4,000 IUs.

That said, I think 1k IUs is considered a standard dose for people without a deficiency. 4k IUs are generally used by people who are currently deficient, or have other issues that cause the deficiency. Doctors will sometimes prescribe doses up to 10k IUs for deficient people.

Re:The First Randomized Controlled Trial on Vitamin D and Co... by LegitShady on Friday September 04, 2020 @11:56AM (#24376092)
Please don't go by what you last heard and instead read the linked paper to get an idea as to how the recommended dosage was arrived at and how statistical errors caused the recommended dosage to be too low.
Re:The First Randomized Controlled Trial on Vitamin D and Co... by LegitShady on Friday September 04, 2020 @11:54AM (#24376076)
Please read the linked paper. The 600 iu dosage recommendation is due to statistical error, and the paper is rather short but goes through it.

200 iu sounds very low.

Re:The First Randomized Controlled Trial on Vitamin D and Co... by raverbashing on Friday September 04, 2020 @01:20AM (#24371934)
High doses can be appropriate as a one off dose for someone with low dosage