The front road (Mt. Hamilton Road / Hwy 130, starting at Alum Rock) is very winding because the grade was limited to allow horse & cargo carriage to summit the peak. Limiting the grade means extra turns. The back side roads, down to Livermore or Patterson, as well as the faster front cutoff (Quimby Rd) were built for vehicles and are much steeper and a little straighter.

Source: Grew up there