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Re:Sendgrid under siege from hacked accounts by jonas21 on Saturday August 29, 2020 @11:38PM (#24321177)
Preventing email spam was in fact the original use case for proof of work.

https://en.wikipedia.org/wiki/Hashcash

Re:Sendgrid under siege from hacked accounts by _heimdall on Sunday August 30, 2020 @03:36AM (#24321962)
This was the inspirstion for nano's use of proof of work too. They don't use PoW for the chain itself but do require every transaction to include a small proof of work to avoid spamming the network, almost identical to hashcash.