With rare exceptions ("The laws of thermodynamics") they didn't write about the sciences, but they were musically a bit more sophisticated and just as witty.
Their satire was far less biting but was present. Although Michael Flanders did monologue: "The purpose of Satire, it has been rightly said, is to strip off the veneer of comforting illusion and cosy half-truth - and our job, as I see it, is to put it back again." :)
I recommend their delightful animal song "The Sloth" as having pertinence to my fellows in the HN audience who have trouble with procrastination...
[0] https://www.youtube.com/watch?v=JwJ4iKv0H70&list=OLAK5uy_m5z...
(It's tempting to recount some here, but I think it's better to hear it from the man himself.)
Happily, although he hasn't performed in decades, Tom Lehrer is still alive today, at the age of 92.
I found three albums of his - "That was the year that was", "An evening wasted with Tom Lehrer" and "Antoher evening wasted". They cover the more famous parts of his repertoire, and for the rest you'll likely have to look through YouTube and the internet.
Highly recommended.