I have a keyboard with a similar arrangement, and I've still never quite gotten used to it. I make extensive use of the Mac's built-in text editing shortcuts, and chording them all gets very confusing.

  Beginning of line: right-fn+cmd+h
  Select beginning of line: right-fn+cmd+right-shift+h
  Previous word: left-fn+option+h
  Select previous word: left-fn+option+left-shift+h

I kept telling myself it would eventually click, but I found myself still making mistakes two weeks in.