The way I see it, psychedelics can be tools you can use to see things you don't normally see, but you still need to be sober afterwards to "clean up" the ideas to allow people who aren't tripping to understand what you mean. A conversation between someone on LSD with someone who is not, will often look like the one on LSD is talking non-sense. If they are both on LSD, they can usually understand each other. If the person on LSD would have gotten sober time before talking to the sober person, they could make the language and ideas more suitable for understanding.

So while Hypercard was initially "invented" under the influence, if they would have kept being on LSD while developing at as, it would have been a mess.