It should theoretically be a lot more scalable to just culture en masse. Since you’re not doing any modifications.

Altho if they required testing of the culture to ensure no mutation that would slow things down

Growing wild-type coronavirus is easier than making the current vaccine approaches? How/Why? As someone familiar with virology and cGMPs, I don’t see how that is the case.

My thinking is that culturing massive amounts is incredibly scalable since there's no need to inactivate or perform other steps to render the virus safe. You're just culturing a fuckton of virus in a medium like agar.

> ramping up the supply of a cold virus inoculation would run into mostly the same challenges

If you can let people actually catch the virus, then can't you avoid a lot of the vaccine production by letting people spread it to each other?