What does Last of Us say about fungi?

In the beginning, Joel will have to move inside confined spaces, thick contamined air fully surrounding him. In order to protect himself, he will put on his old gas mask that he's been using for years. Somehow that's sufficient. The spores apparently don't contaminate his hair, his clothes, his backpack, his weapons. Once he's cleared the area, he simply takes off the mask and moves on.

So I'm not sure if anything of substance can be learned from this game.