A programmer friend of mine broke his arm dirt biking. We took an old Kinesis Freestyle and mounted one side to a tripod with a ball joint. We were able to turn one half of the keyboard on its side so his wrist did not need to face down, which was impossible. It worked out pretty well from what I remember.

Also worth noting, I think most Kinesis keyboards have hardware key remapping. The Advantage definitely does. It's wonderful to not need to rely on software to get your keyboard to do something unusual.