Nubank is a company valued at over $10 billion, with investing from major Silicon Valley firms. It is not unknown to millions of people, and is expanding internationally so I don't think they'll be regional much longer. Clojure and datomic being such a good fit for their tech stack of hundreds of microservices and thousands of databases should really encourage people to use clojure like Erlang's history in telecommunications encouraged people to adopt Elixir.