A perfect example is amphetamines. Without them, I don't get stuff done, sure I will get the one thing done that I am interested in, but the dishes will sit in the sink for 2 weeks before I can even remotely begin to think about them, and then it is like pulling teeth to get started. The task just seems insurmountable. When I take my medicine, I do them as a way to take a break from thinking. I agree, I think a lot of people self-medicate mental health issues. I know I like opiates, so I always take them as prescribed when they are given to me. Never had an addiction problem with them, but I was on them for a period of time due to a back injury. I think the risk of amphetamine addiction is overblown, but I certainly see how opiates can be addictive and very quickly. They make you pretty much not give a crap about anything.