News for hackers. Stuff that matters.
Re:Genes, blood type tied to risk of severe Covid-19 by murphyslab on Thursday June 18, 2020 @03:07PM (#23566514)
23andMe also reported on their blog that their preliminary data also supports a protective role of blood type O:

> Individuals with O blood type are between 9-18% percent less likely than individuals with other blood types to have tested positive for COVID-19, according to the data.

and

> While it is still very early in the study, 23andMe’s preliminary investigation into genetics seems to support these findings. Comparing the research participants who reported that they tested positive for COVID-19 to those who tested negative, our researchers identified a variant in the ABO gene associated with a lower risk. (The single nucleotide polymorphism in the ABO gene is rs505922, a T at that location is associated with lower risk. The P-value for the association is 1.4e-8, OR = 0.88).

See:

* https://blog.23andme.com/23andme-research/23andme-finds-evid... * https://www.snpedia.com/index.php/Rs505922

Re:Genes, blood type tied to risk of severe Covid-19 by hinkley on Thursday June 18, 2020 @03:10PM (#23566559)
With those sort of numbers I kind of wonder if there isn't some other gene that is correlated with type O blood, rather than the blood type itself.
Re:Genes, blood type tied to risk of severe Covid-19 by DoreenMichele on Thursday June 18, 2020 @04:27PM (#23567601)
Given how it impacts the blood (clotting), I don't see any reason to think you need to look for some other explanation beyond blood type.
Re:Genes, blood type tied to risk of severe Covid-19 by zosima on Thursday June 18, 2020 @03:23PM (#23566723)
Why would you think that?

A p-value of 1.4e-8 is significant enough when there is a prior hypothesis. And the odds-ratio looks normal too.