As another poster said with PurgeCSS it isn't bad at all. I'm lucky enough that all my users are internal and we're a Chrome only business so a lot of that cruft can be left out and the speed of the page isn't a large concern.

Prototyping with VueJS and Tailwind on the frontend with Rails on the backend is pretty much my ideal workflow. It's so quick to get a feature done I still surprise myself.