Here's an idea about how to start with the mailbox sensor: https://www.twilio.com/blog/iot-mailbox-sensor-m2m-to-sms-fu.... This one sends an SMS when triggered, but you could certainly add it into Home Assistant too.
Re:Twilio Super Sim – Public Beta
by simcop2387 on Friday June 12, 2020 @06:13PM
(#23504437)
LoRa WAN and such tech can be very useful for this.
Another use may be something like a device that warns if a locked, remote, storage area is accessed. In fact, almost any alarm system that lacks a cellular backup could add one pretty cheaply with this.